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[Sacral recurrence of rectal carcinoma]
1Chirurgische Klinik, RWTH Aachen.
Der Chirurg; Zeitschrift Fur Alle Gebiete Der Operativen Medizen
|October 1, 1995
Summary
Radical resection of recurrent rectal cancer offers significant survival benefits and local tumor control. Surgical intervention, even palliative, improves pain management and life expectancy for patients with locally recurrent rectal cancer.
Area of Science:
- Oncology
- Surgical Oncology
- Gastrointestinal Surgery
Context:
- Locally recurrent rectal cancer presents a significant clinical challenge.
- A substantial proportion of patients are symptomatic at diagnosis.
- Multivisceral resection is frequently required for complete tumor removal.
Purpose:
- To evaluate the outcomes of surgical management for locally recurrent rectal cancer.
- To assess the impact of radical resection versus palliative surgery on survival and local control.
- To determine the role of intraoperative radiation therapy (IORT) in managing recurrent rectal cancer.
Summary:
- A review of 101 patients with recurrent rectal cancer revealed that radical resection, when feasible with negative margins, leads to improved median survival (24 months) and 5-year survival rates (21%) compared to palliative resection (17 months, 13.5%).
- Operative mortality was low (1.1%), though morbidity was higher in patients undergoing exploratory celiotomy (36.3%).
- Both curative and palliative resections provided significant pain relief (81% and 75%, respectively).
Impact:
- Radical resection of recurrent rectal cancer is associated with acceptable mortality and morbidity.
- Surgical intervention effectively palliates local symptoms and improves survival.
- Complete resection with negative margins is crucial for optimal local control and long-term outcomes.