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Endocervical pathogens in women with preterm and term labour
R Nadisauskiene1, S Bergström, I Stankeviciene
1Department of Obstetrics and Gynaecology, Kaunas Medical Academy, Norway.
Gynecologic and Obstetric Investigation
|January 1, 1995
Summary
Certain bacteria, including Escherichia coli and Staphylococcus aureus, are more common in women experiencing preterm labor compared to those in term labor. This finding may help identify risk factors for preterm birth.
Area of Science:
- Obstetrics and Gynecology
- Microbiology
- Perinatal Medicine
Background:
- Preterm labor is a significant concern in maternal and infant health.
- The role of endocervical microflora in preterm labor requires further investigation.
Purpose of the Study:
- To compare endocervical microflora in women with preterm versus term labor.
- To determine if specific microorganisms are associated with preterm labor.
Main Methods:
- Prospective study in Lithuania involving 212 women in preterm labor (latent and active phases) and 62 healthy women in term labor.
- Microbiological assessment included cultures for aerobic bacteria, yeasts, and Trichomonas vaginalis.
- Direct immunofluorescence reaction was used for Chlamydia trachomatis, Escherichia coli, and Staphylococcus aureus detection.
Main Results:
- Escherichia coli (OR 8.16) and Staphylococcus aureus (OR 7.79) were significantly more prevalent in endocervical cultures of women in preterm labor compared to term labor.
- Chlamydia trachomatis prevalence was similar in both preterm and term labor groups.
- Pregnancy outcomes did not differ based on Chlamydia trachomatis infection status in preterm labor phases.
Conclusions:
- Escherichia coli and Staphylococcus aureus are significantly more prevalent in the endocervix of Lithuanian women experiencing preterm labor.
- These bacteria may represent potential risk factors or markers associated with preterm labor.