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Choroid plexus carcinoma in the lateral ventricle--case report
A Hashizume1, Y Kodama, T Hotta
1Department of Neurosurgery, Kure National Hospital, Hiroshima.
Neurologia Medico-Chirurgica
|October 1, 1995
Summary
A 68-year-old male with choroid plexus carcinoma experienced improved symptoms after partial tumor removal and radiation therapy. Treatment led to reduced tumor size and decreased carcinoembryonic antigen levels.
Area of Science:
- Neuro-oncology
- Neurosurgery
- Radiation Oncology
Background:
- Choroid plexus carcinoma is a rare malignant brain tumor, often presenting with neurological deficits.
- Early diagnosis and multimodal treatment are crucial for managing this aggressive neoplasm.
Observation:
- A 68-year-old male presented with dysarthria and gait disturbance due to a left lateral ventricle choroid plexus carcinoma.
- Magnetic resonance imaging revealed a homogeneously enhanced mass in the trigone.
- Arteriography identified the left medial posterior choroidal artery as the tumor's blood supply.
Findings:
- The patient underwent partial tumor resection followed by local linear accelerator (LINAC) radiation therapy (50 Gy).
- Post-treatment, a reduction in the residual tumor size was observed.
- Serum carcinoembryonic antigen levels decreased following irradiation, indicating a positive treatment response.
Implications:
- This case highlights the effectiveness of a combined surgical and radiation approach for localized choroid plexus carcinoma.
- The decrease in carcinoembryonic antigen serves as a potential biomarker for treatment efficacy.
- Further research into optimizing treatment strategies for choroid plexus carcinoma is warranted.