[Xanthelasma of the sigmo-rectal wall]

Xanthelasma is a benign localized collection of lipid-laden histiocytes, that is usually idiopathic and immunohistochemical studies confirmed the histiocytic nature of the proliferation. It is here reported a case in the sigma-rectum, with a review of the recent literature on the argument. Although it is a well recognized entity already described in various organs, its occurrence in the wall of the sigma-rectal channel is at all uncommon. It is suggested that the lesion could be referred to a local immunological disorder, with a cell mediated mechanism.