Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nurses' perceptions of antiemetic effectiveness

V A Rhodes1, R W McDaniel, S G Simms

  • 1Charles and Josie Smith Sinclair School of Nursing, University of Missouri, Columbia, USA.

Oncology Nursing Forum
|September 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Body dysmorphic disorder in patients with anxiety disorders and major depression: a comorbidity study.

The American journal of psychiatry·1995
Same author

Assessment of hibernating myocardium by dobutamine stimulation in a canine model.

Journal of the American College of Cardiology·1995
Same author

Essential thrombocytosis: underemphasized cause of large-vessel thrombosis.

Journal of vascular surgery·1995
Same author

Healing determinants in older people with leg ulcers.

Research in nursing & health·1995
Same author

Selective tumorigenesis in non-parenchymal liver epithelial cell lines by hepatocyte growth factor transfection.

Cancer letters·1995
Same author

Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons.

Neuron·1995

Oncology nurses frequently use ondansetron (Zofran) with other antiemetics for chemotherapy-induced nausea and vomiting. While effective, nurses noted ondansetron

Area of Science:

  • Pharmacology and Oncology Nursing Practice

Background:

  • Chemotherapy-induced nausea, vomiting, and retching (CINV) are significant side effects impacting patient quality of life.
  • Effective antiemetic regimens are crucial for patient tolerance and adherence to cancer treatment protocols.

Purpose of the Study:

  • To identify antiemetic drug combinations used with ondansetron in patients receiving emetogenic chemotherapy.
  • To determine the most frequently administered antiemetic regimens.
  • To ascertain oncology nurses' perceptions of the effectiveness of these antiemetic regimens.

Main Methods:

  • A descriptive survey design was employed.
  • A random sample of 962 Oncology Nursing Society members in the Continental United States participated.
  • The Antiemetic Drug(s)/Drug Combination(s) Inventory questionnaire was mailed to 5,950 oncology nurses.

Related Experiment Videos

Main Results:

  • Ondansetron was part of 70% of all antiemetic regimens and 50% of the most frequently used regimens.
  • Nurses rated first-line antiemetic combinations, including ondansetron, as highly effective.
  • Limitations of ondansetron use included delayed symptom control and high cost.

Conclusions:

  • A variety of antiemetic drugs and combinations are utilized in clinical practice.
  • Ondansetron has demonstrably improved the control of post-chemotherapy nausea, vomiting, and retching.
  • Optimal management of CINV requires skilled nursing assessment, pharmacological knowledge, and patient education.