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Sjögren's syndrome terminating with multiple myeloma
1Department of Central Clinical Laboratory, University of Occupational and Environmental Health, Kitakyushu, Japan.
Scandinavian Journal of Rheumatology
|January 1, 1995
Summary
Sjögren
Area of Science:
- Immunology
- Hematology
- Oncology
Background:
- Sjögren's syndrome (SjS) is an autoimmune disorder.
- Benign monoclonal gammopathy (BMG) is a common finding in SjS.
- Malignant lymphoproliferative disorders can complicate SjS.
Observation:
- A 49-year-old female patient had a 7-year history of SjS and BMG (IgG lambda).
- This patient subsequently developed multiple myeloma (MM).
Findings:
- The co-occurrence of Sjögren's syndrome and multiple myeloma is rare.
- Benign monoclonal gammopathy is frequently observed in SjS patients.
- This case highlights a potential, though uncommon, progression pathway.
Implications:
- Further research into the link between SjS, BMG, and MM is warranted.
- Understanding this association may improve early diagnosis and management strategies.
- This case contributes to the literature on rare SjS complications.