Related Experiment Videos

[Incidence of malignancy in millimetric polyps]

P Vázquez López1, A Herrera Abián, E Molina Pérez

  • 1Unidad de Endoscopia Digestiva, Hospital La Paz, Madrid.

Insights

Excision of all millimetric polyps (≤5 mm) is clinically advised due to a 3.3% rate of high-risk histological changes. This study compared these small polyps to larger ones, finding excision safe and effective.

Area of Science:

  • Gastroenterology
  • Endoscopic Surgery
  • Pathology

Background:

  • Colorectal polyps are common findings during colonoscopy.
  • Millimetric polyps (≤5 mm) represent a significant portion of detected polyps.
  • Histological evaluation is crucial for risk stratification.

Purpose of the Study:

  • To analyze the characteristics and histological findings of millimetric polyps.
  • To compare millimetric polyps with larger polyps (>5 mm).
  • To evaluate the safety and efficacy of endoscopic polypectomy for millimetric polyps.

Main Methods:

  • Retrospective analysis of 178 millimetric polyps and 232 larger polyps from colonoscopies.
  • Data collected included patient demographics, polyp location, morphology, and histological examination.
  • Comparative analysis between millimetric (Group I) and larger (Group II) polyps.

Main Results:

  • Adenomatous polyps were the most frequent histology in both groups (84%).
  • Millimetric polyps showed a higher prevalence of pedunculated/semi-pedunculated morphology compared to sessile in larger polyps.
  • A 3.3% incidence of high-risk histological changes was observed in millimetric polyps, versus 10 in larger polyps.

Conclusions:

  • Endoscopic excision of all millimetric polyps is clinically recommended.
  • The risk of high-risk histological changes in millimetric polyps is not negligible.
  • Polypectomy of millimetric polyps is technically feasible and safe, with no reported complications.

Related Concept Videos