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[Incidence of malignancy in millimetric polyps]
P Vázquez López1, A Herrera Abián, E Molina Pérez
1Unidad de Endoscopia Digestiva, Hospital La Paz, Madrid.
Abstract:
This paper is based on the analysis of 178 polyps of 5 mm or less (polyps we have termed "millimetric") studied in the Endoscopy Department of "La Paz" Hospital, Madrid, during 1993. All polyps fulfilling these characteristics detected during this period are included. The 178 polyps represent 43.4% of all polyps (N = 410) found on colonoscopy in this department in this period. The variables considered in the study protocol include age, sex, localization, morphology and histological examination, with particular attention to high risk histological lesions such as signs of possible malignancy.; we also performed a comparative study between the results obtained from the 178 millimetric polyps (Group I) and the 232 polyps greater than 5 mm (Group II) obtained during the same period. The endoscopic technique for the resection of the polyps was evaluated together with its possible complications. Although there were no significant differences found in respect to age, sex and location, there were morphological differences with a greater number of pediculated or semi-pediculated polyps in Group I whilst there were more sessile polyps in Group II. Adenomatous polyps were the most frequent (84%) in both groups. There was a greater incidence of signs of possible early malignant changes in Group II polyps (10) than in Group I (3.3%). The conclusions which may be drawn from our study are that it is clinically advisable to excise all polyps of 5 mm or less as the frequency of high risk histological changes is not negligible (3.3%), and excision is not problematic as the technique is easy and there have been no complications in our series.
Insights
Excision of all millimetric polyps (≤5 mm) is clinically advised due to a 3.3% rate of high-risk histological changes. This study compared these small polyps to larger ones, finding excision safe and effective.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Pathology
Background:
- Colorectal polyps are common findings during colonoscopy.
- Millimetric polyps (≤5 mm) represent a significant portion of detected polyps.
- Histological evaluation is crucial for risk stratification.
Purpose of the Study:
- To analyze the characteristics and histological findings of millimetric polyps.
- To compare millimetric polyps with larger polyps (>5 mm).
- To evaluate the safety and efficacy of endoscopic polypectomy for millimetric polyps.
Main Methods:
- Retrospective analysis of 178 millimetric polyps and 232 larger polyps from colonoscopies.
- Data collected included patient demographics, polyp location, morphology, and histological examination.
- Comparative analysis between millimetric (Group I) and larger (Group II) polyps.
Main Results:
- Adenomatous polyps were the most frequent histology in both groups (84%).
- Millimetric polyps showed a higher prevalence of pedunculated/semi-pedunculated morphology compared to sessile in larger polyps.
- A 3.3% incidence of high-risk histological changes was observed in millimetric polyps, versus 10 in larger polyps.
Conclusions:
- Endoscopic excision of all millimetric polyps is clinically recommended.
- The risk of high-risk histological changes in millimetric polyps is not negligible.
- Polypectomy of millimetric polyps is technically feasible and safe, with no reported complications.