Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prothymosin alpha: in search of a function

M R Smith1

  • 1Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.

Leukemia & Lymphoma
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pollinators support the nutrition and income of vulnerable communities.

Nature·2026
Same author

Correction to: MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies.

Cell death & disease·2024
Same author

Niraparib plus abiraterone acetate with prednisone in patients with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: second interim analysis of the randomized phase III MAGNITUDE trial.

Annals of oncology : official journal of the European Society for Medical Oncology·2023
Same author

Potential rise in iron deficiency due to future anthropogenic carbon dioxide emissions.

GeoHealth·2020
Same author

Global Health Implications of Nutrient Changes in Rice Under High Atmospheric Carbon Dioxide.

GeoHealth·2020
Same author

Bacterial community structure and response to nitrogen amendments in Lake Shenandoah (VA, USA).

Water science and technology : a journal of the International Association on Water Pollution Research·2019

Prothymosin alpha, a nuclear protein, is linked to cell proliferation. Its exact function is unknown, but it

Area of Science:

  • Molecular Biology
  • Cell Biology
  • Biochemistry

Background:

  • Prothymosin alpha is an acidic nuclear protein found in many cell types.
  • Its expression levels correlate with cell proliferation states.
  • Prothymosin alpha is highly conserved across species, suggesting a critical role.

Purpose of the Study:

  • To investigate the role of prothymosin alpha in cell proliferation.
  • To explore potential pathways involving prothymosin alpha, such as the c-myc pathway.

Main Methods:

  • Analysis of prothymosin alpha expression levels in various cell types.
  • Correlation studies between prothymosin alpha expression and cellular proliferation rates.
  • Investigating potential interactions with known proliferation-associated proteins.

Related Experiment Videos

Main Results:

  • Prothymosin alpha is expressed at high levels in diverse cell types.
  • Data suggests a correlation between prothymosin alpha expression and cell proliferation.
  • Evidence indicates prothymosin alpha may be essential for proliferation and potentially linked to the c-myc pathway.

Conclusions:

  • Prothymosin alpha plays a significant role in regulating cell proliferation.
  • While its precise function is yet to be fully elucidated, it is likely critical for cellular growth.
  • Further research is needed to understand the exact molecular mechanisms of prothymosin alpha.