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[Myocardial contractility during angina pectoris attack in ischemic heart disease]
Kardiologiia
|January 1, 1977
Summary
Physical exercise can reduce myocardial function in patients experiencing angina pectoris. Two distinct hemodynamic responses were observed during ischemic events, impacting heart volumes and ejection fraction.
Area of Science:
- Cardiology
- Exercise Physiology
- Echocardiography
Context:
- Studied myocardial contractility in 42 male patients undergoing graded physical exercise.
- Patients developed documented angina pectoris with ischemic ECG changes at peak exercise.
- Angina decubitus attacks also showed similar changes in some patients.
Purpose:
- To investigate the impact of angina pectoris attacks during physical exertion on myocardial contractility.
- To characterize hemodynamic reactions associated with myocardial ischemia during exercise.
Summary:
- Anginal attacks were accompanied by a reduction in myocardial function.
- Two hemodynamic reaction types were identified during myocardial ischemia.
- Type 1: Increased end-systolic and end-diastolic volumes, unchanged stroke volume, decreased ejection fraction (normal initial heart volume).
- Type 2: Decreased end-diastolic and stroke volumes, altered end-systolic volume, further decreased ejection fraction (increased initial heart volume).
Impact:
- Provides insights into the functional consequences of myocardial ischemia during physical stress.
- Differentiates hemodynamic responses based on initial heart volume in ischemic heart disease patients.
- Highlights the detrimental effect of angina on cardiac performance and ejection fraction.