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High intensity focused ultrasound for benign prostatic hyperplasia
T Uchida1, E Yokoyama, M Iwamura
1Department of Urology, Kitasato University School of Medicine, Sagamihara, Japan.
Summary
Transrectal high intensity focused ultrasound (HIFU) shows promise for treating benign prostatic hyperplasia (BPH), improving symptoms and quality of life. Further research is needed to confirm its long-term effectiveness compared to traditional treatments.
Area of Science:
- Urology
- Medical Technology
- Oncology
Background:
- Transurethral resection of the prostate (TURP) is the standard treatment for symptomatic benign prostatic hyperplasia (BPH).
- Transrectal high intensity focused ultrasound (HIFU) is explored as an alternative treatment for symptomatic BPH.
Purpose of the Study:
- To evaluate the safety and effectiveness of transrectal high intensity focused ultrasound (HIFU) for treating symptomatic benign prostatic hyperplasia (BPH).
Main Methods:
- HIFU treatment was administered to 28 BPH patients.
- Patients were assessed at 1, 3, and 6 months post-treatment using International Prostate Symptom Scores (I-PSS), Quality of Life (QOL) surveys, uroflowmetry, and transrectal ultrasound for prostate volume.
Main Results:
- Statistically significant improvements in I-PSS and QOL were observed at 1, 3, and 6 months post-HIFU (P < 0.0001-0.005).
- Treatment effectiveness rates were 35.7% at 1 month, 46.4% at 3 months, and 40.0% at 6 months.
Conclusions:
- High intensity focused ultrasound (HIFU) offers a novel approach for tissue ablation, potentially sparing surrounding structures.
- Further development and longer follow-up are necessary to optimize HIFU parameters and establish its long-term efficacy for BPH treatment.