The effects of time point alignment on the amplitude of averaged orbital presaccadic spike potential (SP)

Effects of two time-point selection averaging techniques on orbital SP amplitude were studied on 10 normal subjects performing horizontal saccades. One technique involved averaging from the SP peak, another technique involved averaging from the saccadic onset. The time-point selection methods only affected the magnitude of SP amplitude but did not interact with experimental conditions. Repeated measures analysis of variance showed that SP amplitudes were higher in data aligned on SP peak than those aligned on saccadic onset (P < 0.01). No significant second order (saccade by degree) or third order (saccade by direction) interactions involving averaging method were found (P > 0.05).