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The effect of nasolacrimal occlusion on drug-induced mydriasis
A Loewenstein1, A Sadeh, M Goldstein
1Department of Ophthalmology, Ichilov Hospital, Tel-Aviv, Israel.
Abstract
Background:
Nasolacrimal occlusion has been shown to improve the efficacy of some topically applied ocular drugs. The aim of this study was to investigate the effect of nasolacrimal occlusion on tropicamide-induced mydriasis.
Methods:
We compared pupillary dilatation by 0.125% tropicamide with and without nasolacrimal occlusion in 40 healthy volunteers.
Results:
Analysis of variance with repeated measures failed to show any advantage due to nasolacrimal occlusion in drug-induced mydriasis.
Conclusion:
Nasolacrimal occlusion did not increase the mydriasis obtained with 0.125% tropicamide.