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Necrotizing sarcoid granulomatosis: computed tomography and pathologic findings
H Niimi1, T E Hartman, N L Müller
1Department of Radiology, University of British Columbia and Vancouver Hospital, Vancouver.
Objective:
To describe the CT findings and corresponding pathological findings of necrotizing sarcoid granulomatosis (NSG).
Materials And Methods:
We reviewed the high-resolution CT and macroscopic and histologic findings in three pathologically proven cases of NSG.
Results:
The CT findings consisted of one case each with single nodule, multiple nodules, and parenchymal opacification. The abnormalities were peribronchovascular or subpleural in distribution. Histologically, all patients had sarcoid-like granulomas with central necrosis and granulomatous vasculitis. The CT findings correlated closely with the gross pathologic findings.
Conclusion:
We conclude that the CT manifestations of NSG reflect the variable macroscopic pathologic findings.