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Necrotizing sarcoid granulomatosis: computed tomography and pathologic findings
H Niimi1, T E Hartman, N L Müller
1Department of Radiology, University of British Columbia and Vancouver Hospital, Vancouver.
Journal of Computer Assisted Tomography
|November 1, 1995
Summary
Necrotizing sarcoid granulomatosis (NSG) CT findings correlate with pathological features. High-resolution CT can reveal nodules or opacities reflecting necrotizing sarcoid granulomatosis pathology.
Area of Science:
- Radiology
- Pathology
- Pulmonology
Background:
- Necrotizing sarcoid granulomatosis (NSG) is a rare granulomatous disease.
- Understanding its imaging features is crucial for diagnosis.
Purpose of the Study:
- To correlate computed tomography (CT) findings with pathological findings in NSG.
Main Methods:
- Review of high-resolution CT, macroscopic, and histologic findings.
- Analysis of three pathologically confirmed cases of NSG.
Main Results:
- CT findings included single nodule, multiple nodules, and parenchymal opacification.
- Abnormalities showed peribronchovascular or subpleural distribution.
- Histology revealed sarcoid-like granulomas with central necrosis and vasculitis.
Conclusions:
- CT manifestations of NSG align with variable macroscopic pathological findings.
- Imaging findings aid in the diagnosis of necrotizing sarcoid granulomatosis.