Multiple oncocytic laryngeal cysts presenting as acute airway obstruction

Solitary oncocytic cyst of the larynx is a recognized clinical and pathologic entity. Multiple oncocytic cysts have only rarely been described. A 67-year-old female presented with rapidly progressive airway obstruction requiring emergency tracheotomy. The obstruction was caused by multiple cystic lesions throughout the supraglottic region. Microscopic examination of laryngeal biopsies showed cysts within the lamina propria, lined by oncocytic epithelium. The differential diagnosis and pathogenesis of oncocytic cysts is discussed with a review of other laryngeal cystic lesions.