Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Multiple endocrine neoplasia type I]

S Kawa1, Y Karasawa, H Oguchi

  • 1Second Department of Internal Medicine, Shinshu University School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Uterine sutures at prior caesarean section and placenta accreta in subsequent pregnancy: a case-control study.

BJOG : an international journal of obstetrics and gynaecology·2014
Same author

An infrared imaging method for high-throughput combinatorial investigation of hydrogenation-dehydrogenation and new phase formation of thin films.

The Review of scientific instruments·2009
Same author

Model, prediction, and experimental verification of composition and thickness in continuous spread thin film combinatorial libraries grown by pulsed laser deposition.

The Review of scientific instruments·2007
Same author

In vitro effect of nanoleakage expression on resin-dentin bond strengths analyzed by microtensile bond test, SEM/EDX and TEM.

Biomaterials·2004
Same author

Degradation of resin-dentin bonds using NaOCl storage.

Dental materials : official publication of the Academy of Dental Materials·2003
Same author

Autosomal-dominant hypoplastic form of amelogenesis imperfecta caused by an enamelin gene mutation at the exon-intron boundary.

Journal of dental research·2002
Same journal

[Development of novel therapeutics for multiple myeloma and improvement of drug lag].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Clinical pharmacy services to patients of immunomodulatory drugs].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Therapeutic drug monitoring of the new anti-myeloma drugs in the treatment of multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Prognostic value of minimal residual disease assessment using next-generation sequencing in multiple myeloma].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[The evaluation of minimal residual disease in multiple myeloma by an allele-specific oligonucleotide real-time PCR].

Nihon rinsho. Japanese journal of clinical medicine·2019
Same journal

[Evaluation of minimal residual disease in myeloma by multiparametric flow cytometry].

Nihon rinsho. Japanese journal of clinical medicine·2019
See all related articles

Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder causing tumors in the parathyroid, pancreas, and pituitary. Identifying gene carriers through genetic markers allows for earlier intervention to manage MEN1 syndrome manifestations.

Area of Science:

  • Endocrinology and Genetics
  • Molecular Biology
  • Cancer Genetics

Context:

  • Multiple Endocrine Neoplasia type 1 (MEN1) is a rare autosomal dominant disorder.
  • MEN1 is characterized by primary hyperparathyroidism, pancreatic endocrine tumors, and anterior pituitary neoplasms.
  • The genetic basis of MEN1 has been linked to chromosome 11q3, but the specific gene remains elusive.

Purpose:

  • To summarize the current understanding of Multiple Endocrine Neoplasia type 1 (MEN1).
  • To highlight the diagnostic challenges and the importance of genetic linkage studies in MEN1.
  • To emphasize the potential for early intervention in MEN1 management.

Summary:

  • MEN1 is an inherited endocrine neoplasia syndrome with high penetrance.
  • Linkage analysis has localized the MEN1 gene to chromosome 11q3.

Related Experiment Videos

  • Molecular genetic markers are crucial for identifying gene carriers within affected families.

    • Impact:

    • Early identification of gene carriers enables timely therapeutic or prophylactic interventions.
    • Proactive management can mitigate severe manifestations of MEN1, such as gastrointestinal bleeding or malignant transformation.
    • Advances in genetic marker analysis improve the clinical management and prognosis for MEN1 patients.