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[The function and role of extrathymic T cells]

S Seki¹, K Takeda, T Abo

¹Department of Pediatrics, Sendai Hospital of Nation Defense Force.

Nihon Rinsho. Japanese Journal of Clinical Medicine

|November 1, 1995

Summary

Murine liver contains unique T cells (TCRint) that, when activated by IL-12, gain NK1 expression and cytotoxicity. These CD4+ NK1high TCRint cells effectively inhibit tumor metastasis in mice.

Area of Science:

Immunology
Cell Biology
Cancer Research

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