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Functional bladder capacity measured during radionuclide cystography in children
S T Treves1, D Zurakowski, S B Bauer
1Department of Radiology, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Radiology
|January 1, 1996
Summary
Functional bladder capacity (FBC) in children increases with age, following a nonlinear curve. Girls and children with reflux tend to have larger FBC, independent of height and weight.
Area of Science:
- Pediatric urology
- Nuclear medicine
- Biostatistics
Background:
- Functional bladder capacity (FBC) is a critical metric in pediatric urology.
- Understanding FBC development is essential for diagnosing and managing bladder dysfunction.
- Direct radionuclide cystography (DRC) is a valuable tool for assessing FBC.
Purpose of the Study:
- To estimate functional bladder capacity (FBC) in children using direct radionuclide cystography (DRC).
- To determine the relationship between FBC and patient age.
- To investigate the association between vesicoureteral reflux (VUR) and FBC.
Main Methods:
- Analysis of 5,165 DRC studies in patients aged 0–14 years.
- Development of nonlinear models to estimate FBC based on age.
- Separate analysis for boys and girls, with evaluation of height and weight as predictors.
Main Results:
- A nonlinear power function best describes the relationship between FBC and age.
- Girls and patients with VUR demonstrated significantly larger FBC when age was controlled (P < .01).
- Height and weight did not enhance the accuracy of FBC prediction.
Conclusions:
- FBC in children exhibits a nonlinear, age-dependent growth pattern.
- The observed nonlinear relationship supports the concept of bladder maturation in infants and children.
- Vesicoureteral reflux may be associated with increased FBC in pediatric populations.