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Related Experiment Videos

Urothelial striations revisited

M D Parker1, R L Clark

  • 1Department of Radiology, University of North Carolina Hospitals, Chapel Hill, USA.

Radiology
|January 1, 1996
PubMed
Summary
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Low-osmolality contrast media (LOCM) in urography significantly increases the occurrence of urothelial striations in healthy adults. This finding is likely due to reduced urinary tract distention associated with LOCM use.

Area of Science:

  • Radiology
  • Urology
  • Medical Imaging

Background:

  • Urography is a common diagnostic procedure.
  • Contrast media are used to enhance visualization of the urinary tract.
  • The osmolality of contrast media may influence imaging findings.

Purpose of the Study:

  • To determine if low-osmolality contrast media (LOCM) increase the frequency of urothelial striations during urography in adults.
  • To compare the incidence of striations between LOCM and high-osmolality contrast media (HOCM).

Main Methods:

  • Retrospective review of 207 adult urograms from two institutions.
  • Urograms were obtained after administration of either LOCM (106 patients) or HOCM (101 patients).
  • Evaluation of radiographs for the presence and extent of urothelial striations.

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Main Results:

  • Striations were observed in 15% of LOCM urograms versus 2% of HOCM urograms (P < .002).
  • The difference in striation frequency between the two groups was statistically significant.
  • Striations were most prevalent in the renal pelvis, distal ureters, and on post-voiding radiographs.

Conclusions:

  • Urothelial striations are frequently detected in adults undergoing urography with LOCM and are typically a normal finding.
  • The increased prevalence of striations with LOCM is likely attributed to decreased urinary tract distention.
  • LOCM use impacts the interpretation of urographic findings related to urothelial integrity.