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Erythroderma: analysis of 247 cases

C Vasconcellos¹, P P Domingues, V Aoki

¹School of Medicine, University of S. Paulo, Brazil.

Revista De Saude Publica

|June 1, 1995

Summary

Erythroderma, a severe skin condition, was most commonly linked to psoriasis, drug reactions, or reticulosis. Repeated skin biopsies are crucial for diagnosing the underlying cause of erythroderma.

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Area of Science:

Dermatology
Clinical Medicine
Epidemiology

Background:

Erythroderma is a significant dermatological condition characterized by widespread erythema and scaling.
Understanding the etiological profile of erythroderma is essential for effective patient management and treatment strategies.

Observation:

A 23-year analysis of 247 patients with erythroderma (duration >2 months) was conducted.
Patient ages ranged from 16 to 60 years, with a male-to-female ratio of 2:1.
Common presentations included diffuse erythema, scaling, and pruritus.

Findings:

Psoriasis was the most frequent underlying cause (44.9%), followed by drug reactions (7.3%) and reticulosis (4.1%).
In 29.2% of cases, the specific cause of erythroderma remained undetermined.
Skin biopsies, particularly repeated ones, were diagnostic or suggestive in 63.6% of cases, highlighting their importance in etiological diagnosis.

Implications:

Repeated skin biopsies are recommended as the optimal method for the etiological diagnosis of erythroderma.
The observed male predominance suggests potential sex-specific environmental exposures contributing to erythroderma development.

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