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Efficacy of ICAM-1 antisense oligonucleotide in pancreatic islet transplantation

S M Katz1, B Browne, T Phan

  • 1University of Texas Medical School, Houston 77030, USA.

Significant islet allograft prolongation was achieved by ICAM-1/LFA-1 blockade. ICAM-1 antisense oligonucleotide IP-3082 was effective in improving islet function as well as prolonging graft survival.

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