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Macrolipasemia and celiac disease

M Garcia-Gonzalez1, V Defarges-Pons, A Monescillo

  • 1Gastroenterology Department, Ramón y Cajal Hospital, Madrid, Spain.

The American Journal of Gastroenterology
|December 1, 1995
PubMed
Summary

This report details a rare case of undiagnosed celiac disease co-occurring with macrolipasemia and macroamylasemia, an association documented only once before. The study reviews existing literature on these conditions.

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Area of Science:

  • Gastroenterology
  • Clinical Biochemistry

Background:

  • Celiac disease is an autoimmune disorder triggered by gluten ingestion.
  • Macroamylasemia and macrolipasemia are rare conditions characterized by high molecular weight forms of amylase and lipase, respectively.

Observation:

  • A unique case presenting with undiagnosed celiac disease, macroamylasemia, and macrolipasemia is described.
  • This specific combination of conditions is exceptionally rare in medical literature.

Findings:

  • The co-occurrence of celiac disease with both macroamylasemia and macrolipasemia is highlighted.
  • A review of previous case reports on macroamylasemia and celiac disease, and macrolipasemia is provided.

Implications:

  • This case expands the understanding of potential associations with celiac disease.

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  • Further research may elucidate sharedPathophysiological mechanisms or diagnostic considerations.