Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diverticular disease-associated chronic colitis

L M Makapugay1, P J Dean

  • 1Department of Pathology, Baptist Memorial Hospital, Memphis, TN 38146, USA.

The American Journal of Surgical Pathology
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic radiofrequency ablation for Barrett's esophagus: 5-year outcomes from a prospective multicenter trial.

Endoscopy·2010
Same author

Committal of a patient due to media influence? A case report.

The Australian and New Zealand journal of psychiatry·2001
Same author

The role of Yersinia enterocolitica and Yersinia pseudotuberculosis in granulomatous appendicitis: a histologic and molecular study.

The American journal of surgical pathology·2001
Same author

Hepatitis C infection among survivors of childhood cancer.

Blood·2000
Same author

Alcohol misuse in clinical forensic medicine.

Journal of clinical forensic medicine·1997
Same author

Low prevalence of human papillomavirus infection in esophageal squamous cell carcinomas from North America: analysis by a highly sensitive and specific polymerase chain reaction-based approach.

Human pathology·1997
Same journal

Clinicopathologic and Molecular Analysis of Traditional Serrated Adenoma and Its Possible Precursor Lesions With Special Reference to RSPO Fusion Status: A Large Case Series From Single Institution.

The American journal of surgical pathology·2026
Same journal

NF2/Merlin Immunohistochemistry Helps Distinguish Collecting Duct Carcinoma From Upper Tract Urothelial Carcinoma.

The American journal of surgical pathology·2026
Same journal

Neuroendocrine Carcinoma of the Gallbladder: Clinicopathologic and Immunohistochemical Analysis of 31 Cases.

The American journal of surgical pathology·2026
Same journal

Papillary Renal Neoplasm With Reverse Polarity Is a Distinct Distal Nephron-Derived Tumor With Unique Methylation Profile.

The American journal of surgical pathology·2026
Same journal

Biallelic ARID1A Alterations: A Promising Novel Biomarker for Risk Stratification and Management in Pediatric Malignant Hepatocellular Tumors.

The American journal of surgical pathology·2026
Same journal

Absent Cyclin D1 Expression in Myeloid Sarcomas Distinguishes From Malignant Histiocytic Neoplasms: When Morphologic Ambiguity is Deceptive.

The American journal of surgical pathology·2026
See all related articles

Diverticular disease can cause chronic sigmoid colitis with inflammation mimicking inflammatory bowel disease. This condition increases the risk of sigmoid colon resection and may precede ulcerative proctosigmoiditis.

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pathology

Background:

  • A unique clinical syndrome of chronic colitis affecting the sigmoid colon in patients with diverticular disease has been reported.
  • The histopathological features of this condition remain incompletely understood.

Purpose of the Study:

  • To analyze the clinical and pathological characteristics of diverticular disease-associated chronic colitis.
  • To differentiate this entity from other forms of colitis and assess its clinical outcomes.

Main Methods:

  • Retrospective analysis of 23 patients with diverticular disease-associated chronic colitis.
  • Review of clinical presentations, colonoscopic findings, and histopathological features from mucosal biopsies.
  • Comparison of outcomes with a control group of patients with diverticular disease without colitis.

Related Experiment Videos

Main Results:

  • Patients commonly presented with hematochezia and sigmoid colon inflammation with features resembling idiopathic inflammatory bowel disease.
  • Histopathology revealed plasmacellular/eosinophilic expansion, cryptitis, crypt abscesses, and distorted crypt architecture.
  • Patients with colitis had a statistically significant increased risk of sigmoid colonic resection (p = 0.049) compared to controls.

Conclusions:

  • Diverticular disease-associated chronic sigmoid colitis exhibits morphological features of idiopathic inflammatory bowel disease but has distinct clinical and endoscopic profiles.
  • This condition is associated with an elevated risk of sigmoid colonic resection.
  • It may precede the development of conventional ulcerative proctosigmoiditis in some individuals.