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Published on: June 15, 2011
Genetic heterogeneity study of non-syndromic autosomal recessive sensorineural deafness within the Tunisian
H Chaabani1, S Ben Arab, K Chebbi
1Faculté de Pharmacie, Monastir, Tunisia.
Abstract:
The number of loci for non-syndromic autosomal recessive sensorineural (N-SARS) deafness, was estimated within the Tunisian population and compared to that obtained in other populations. 30 deaf couples have been collected from 4 governorates (2,318,900 inhabitants) and 3 villages. Our investigations in these regions show that the percentage of congenitally deaf persons which marry each other is exceptionally low (10-30%). The number of loci for N-SARS deafness in the governorates sample was estimated at 8.3. Results could provide data for genetic counseling and facilitate our research concerning the localization of the different loci for N-SARS deafness present in Tunisian population.
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