Related Experiment Videos
Resistance of Candida albicans biofilms to antifungal agents in vitro
1Laboratory of Microbiology, University of Glasgow, United Kingdom.
Antimicrobial Agents and Chemotherapy
|September 1, 1995
Abstract:
Biofilms formed by Candida albicans on small discs of catheter material were resistant to the action of five clinically important antifungal agents as determined by [3H]leucine incorporation and tetrazolium reduction assays. Fluconazole showed the greatest activity, and amphotericin B showed the least activity against biofilm cells. These findings were confirmed by scanning electron microscopy of the biofilms.