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Updated: Aug 19, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
High school students who use crack and other drugs
1Department of Psychiatry, Columbia University, New York, NY, USA.
Background:
When it appeared in the 1980s, crack was thought to represent a completely new pathway of entry into drug use. Our objective was to identify the distinguishing characteristics of adolescents who have reached different stages of drug use, in particular the highest state represented by crack.
Methods:
Adolescents (N = 7611) representative of students in grades 7 to 12 from 53 New York state schools were classified in the following six mutually exclusive, cumulative categories of drug use: nonusers; alcohol and/or cigarette users only; marijuana users only; users of illicit drugs other than marijuana but neither cocaine nor crack; cocaine but not crack users; and crack users. The groups were compared in level of psychosocial functioning.
Results:
Students who use illicit drugs show deficits in school performance, quality of family relationships, and health and increased psychological symptoms. Compared with nonusers, they are more delinquent and more actively involved with their peers and live in social environments in which the perceived use of drugs by other adolescents and parents is more extensive. Delinquency and extent of perceived drug use consistently increase with each higher stage of use. Crack users exhibit the lowest level of psychosocial functioning of any drug-using group.
Conclusions:
There are stage-specific characteristics and common characteristics (delinquent participation, peer drug use) throughout the developmental sequence of drug use. Despite declines over the last two decades in the prevalence of the use of different drugs, young people who use drugs display characteristics over historical time similar to those of young drug users 20 years ago.
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