Clinical and CT evaluation of a new stretch polytetrafluoroethylene aortic graft

A new stretch polytetrafluoroethylene (PTFE) aortic graft became available for clinical use in early 1991. We prospectively evaluated our first 107 stretch aortic PTFE grafts by means of serial CT imaging and compared them with a cohort of concurrently placed Dacron grafts. Stretch PTFE requires no preclotting and is claimed to resist long-term dilation and conform well to anastomoses. Consecutive patients undergoing placement of stretch PTFE grafts were seen at least yearly. Within the first 2 years after implantation, contrast-enhanced CT scans of the abdomen and pelvis were obtained. Caliper measurements were made of the native arteries and the body and any limbs of the aortic grafts. Graft elongation was assessed by noting distortions from the normally circular or minimally ovoid configuration of the grafts on transverse CT images. Indications for grafting were elective repair of abdominal aortic aneurysm in 60 patients, aortoiliac occlusive disease in 31, both aneurysm and occlusive disease in eight, and ruptured abdominal aortic aneurysm in eight. The overall operative mortality rate was 6.5%. There were two early postoperative graft limb thromboses resulting from hypercoagulable states, and there was one graft infection. Mean follow-up was 14.1 months (range 1 to 34 months). CT scans were obtained from 61 patients with stretch PTFE grafts and 10 with concomitantly placed Dacron grafts. Ten patients had two or more postoperative CT scans. Primary stretch PTFE patency was 98% and secondary patency, 100%. There was significantly less dilation of both the graft body and limbs in the stretch PTFE group (body mean 16.5%, range 6.3% to 28.1%; limb mean 19.3%, range 10% to 43%) compared to the Dacron group (body mean 33%, range 22% to 78%; limb mean 62%, range 12.5% to 88.9%) (p < 0.01, unpaired t test).(ABSTRACT TRUNCATED AT 250 WORDS)