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Noninfectious inflammatory response to gold weight eyelid implants
R L Bair1, G J Harris, D B Lyon
1Department of Ophthalmology, Medical College of Wisconsin, Milwaukee 53226, USA.
Ophthalmic Plastic and Reconstructive Surgery
|September 1, 1995
Summary
Noninfectious inflammatory reactions to gold weight eyelid implants can occur, causing gradual eyelid swelling and redness. Local corticosteroid injections may help manage inflammation, potentially allowing implant retention.
Area of Science:
- Ophthalmology
- Biomaterials Science
Background:
- Gold weight implants are used for eyelid closure in conditions like facial nerve palsy.
- Complications associated with these implants are typically mechanical or infectious.
Observation:
- Three patients developed delayed, noninfectious inflammatory reactions to gold weight eyelid implants.
- Symptoms included progressive eyelid edema and erythema, appearing 3-5 weeks post-implantation.
Findings:
- Histopathology revealed a dense eosinophilic coagulum at the tissue-gold interface and a lymphocytic infiltrate.
- Management strategies varied, including implant removal, replacement with platinum, or local corticosteroid injection.
Implications:
- Gold weight implants can trigger a delayed, progressive inflammatory response.
- Local corticosteroid injections may be effective in managing this inflammation, potentially avoiding implant removal.