Chronic cholecystitis with features of diffuse inflammatory pseudotumour: a clinico-pathological case study and...

A case of chronic cholecystitis with features of inflammatory pseudotumour is presented. The patient, a 69-year-old man, was admitted for epigastric pain, nausea, vomiting, and fever. Ultrasound examination of the abdomen revealed diffuse thickening of the gallbladder wall, and numerous calculi inside, without dilatation of the intra and extrahepatic biliary ducts. Cholecystectomy was performed. Histological examination confirmed the diffuse thickening of gallbladder wall, revealing a diffuse chronic inflammatory process with a huge fibroblastic and myofibroblastic proliferation associated with plasma cells, lymphocytes, macrophages, granulocytes, and rare giant multinucleated cells. Only one similar case has been quoted in the literature so far.