Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Toxic neuropathies

A P Mizisin1, H C Powell

  • 1Veterans Administration Medical Center, San Diego, California, USA.

Current Opinion in Neurology
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

Researchers are investigating neurotoxic effects from various substances, including metals and drugs. Studies explore treatments for drug-induced neuropathies and nerve regeneration, offering insights into physiological mechanisms.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab).

Journal of the peripheral nervous system : JPNS·2014
Same author

On-body inertial sensing and signal processing for clinical assessment of tremor.

IEEE transactions on biomedical circuits and systems·2013
Same author

Severe myositis associated with Sarcocystis spp. infection in 2 dogs.

Journal of veterinary internal medicine·2011
Same author

Recurrent demyelination and remyelination in 37 young Bengal cats with polyneuropathy.

Journal of veterinary internal medicine·2011
Same author

Diabetes induces changes in ILK, PINCH and components of related pathways in the spinal cord of rats.

Brain research·2010
Same author

Spinal phospholipase A2 in inflammatory hyperalgesia: role of the small, secretory phospholipase A2.

Neuroscience·2005
Same journal

Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Current opinion in neurology·2026
Same journal

Editorial introduction.

Current opinion in neurology·2026
Same journal

Multimodal mapping of balance dysfunction in Parkinson's disease: a consensus roadmap for research and intervention.

Current opinion in neurology·2026
Same journal

Tourette syndrome: brain neurophysiology, circuit dysfunction, and neuromodulation across invasive and noninvasive approaches.

Current opinion in neurology·2026
Same journal

Dystonia: from phenotypes to genetics and therapeutic advances.

Current opinion in neurology·2026
Same journal

What can we learn from eye movements in movement disorders and Parkinson's disease?

Current opinion in neurology·2026
See all related articles

Area of Science:

  • Neuroscience
  • Toxicology
  • Pharmacology

Background:

  • Neurotoxic effects stem from diverse agents like metals, pharmaceuticals, and environmental substances.
  • Epidemiological methods are evolving to identify lead exposure victims.
  • Methylcobalamin is being studied for acrylamide toxicity amelioration.

Purpose of the Study:

  • To review current understanding of neurotoxic effects and emerging management strategies.
  • To highlight advancements in treating drug-induced neuropathies and enhancing nerve regeneration.
  • To underscore the utility of experimental toxins in elucidating physiological processes.

Main Methods:

  • Review of current publications on neurotoxicology.
  • Exploration of therapeutic interventions for neurotoxicity.

Related Experiment Videos

  • Analysis of experimental studies on nerve regeneration and axonal transport.

    • Main Results:

    • Lead toxicity is being addressed with new epidemiological methods.
    • Methylcobalamin shows potential for mitigating acrylamide toxicity.
    • Adjustments in dosage may manage neuropathic effects of antiarrhythmic and antilipidemic drugs.
    • Hormone analogs and neurotrophic factors aid in managing chemotherapy-induced neurotoxicity.
    • FK 506, an immunosuppressant, has documented peripheral neuropathy side effects but may accelerate nerve regeneration.
    • Botulinum toxin is effective for spastic disorders, requiring training.
    • Experimental toxins like imminodipropionitrile provide insights into axonal transport.

    Conclusions:

    • Ongoing research addresses diverse neurotoxic agents and their management.
    • Therapeutic strategies are evolving for drug-induced neuropathies and nerve damage.
    • Experimental models remain crucial for understanding fundamental neurophysiological mechanisms.