Hepatoid adenocarcinoma of the stomach: a case report

A case of primarily inoperable hepatoid adenocarcinoma of the stomach is reported, which, after chemotherapy with farmorubicin, 5-fluorouracil and leucovorin, showed an impressive regression resulting in an improvement of the overall condition of the patient and a decrease of the serum AFP level from initially 79.120 ng/ml to 3.728 ng/ml. In a second operation the tumor was removed and intraoperative radiation therapy was applied to the head of the pancreas and intraabdominal lymph nodes. Furthermore, we discuss the main pathologic features of this rare tumor entity and give a short review of the literature.