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Related Experiment Videos

[Primary pulmonary amyloidosis with multiple nodules]

Y Shinohara1, Y Jinn, H Tachi

  • 1Department of Internal Medicine, Tuchiura Kyodo Hospital, Ibaraki, Japan.

Nihon Kyobu Shikkan Gakkai Zasshi
|October 1, 1995
PubMed
Summary

Pulmonary amyloidosis can be produced by foreign body giant cells, not just plasma cells. This study identifies amyloid star formations within these cells, suggesting a novel mechanism for amyloid deposition in the lungs.

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Area of Science:

  • Pulmonary Medicine
  • Pathology
  • Cell Biology

Background:

  • Amyloidosis is characterized by extracellular deposition of misfolded proteins.
  • Pulmonary amyloidosis presents with various symptoms including cough and dyspnea.
  • Traditionally, plasma cells are considered the primary source of amyloid-producing light chains.