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[Multiple (visceral and neurologic) tumors]

P Giraud1, P Petiot, A Vighetto

  • 1Service de Neurologie, Hôpital Neurologique Pierre Wertheimer, Lyon.

Presse Medicale (Paris, France : 1983)
|December 2, 1995
PubMed
Summary

This study found that while the association between breast cancer and meningioma is rare, malignant melanoma frequently co-occurs with central nervous system tumors. This highlights the importance of histological confirmation for brain tumors.

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Area of Science:

  • Neurology
  • Oncology
  • Epidemiology

Context:

  • Investigating the co-occurrence of central nervous system (CNS) and visceral tumors.
  • Analyzing epidemiological features, histology, and temporal delays between primary and secondary neoplasms.
  • Examining associations between neurological and non-neurological malignancies.

Purpose:

  • To determine the frequency and characteristics of associated neurological and visceral tumors.
  • To identify specific tumor type associations, such as CNS tumors with visceral malignancies.
  • To establish guidelines for diagnosing CNS tumors following a visceral tumor diagnosis.

Summary:

  • The study analyzed 11 patients with concurrent or sequential CNS and visceral tumors over a 20-year period.
  • Meningioma and glioma were the most common CNS tumors, while malignant melanoma was frequent among visceral malignancies.
  • A significant association was observed between malignant melanoma and CNS tumors, contrasting with the absence of the typical breast cancer-meningioma link.

Impact:

  • Findings underscore the frequency of associated neoplasia, emphasizing the need for thorough patient evaluation.
  • Highlights a potential link between malignant melanoma and CNS tumors, warranting further investigation.
  • Stresses the importance of histological confirmation to differentiate primary CNS tumors from metastases.

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