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Peritonitis due to Penicillium sp in a patient receiving continuous ambulatory peritoneal dialysis
1Department of Medical Education, Methodist Hospitals of Memphis, Tenn., USA.
Abstract:
Infectious peritonitis is a common complication of continuous ambulatory peritoneal dialysis (CAPD). Only one case of CAPD-related peritonitis due to Penicillium sp has previously been reported. We present a second case in which fungal colonies were observed on the inner surface of the CAPD catheter. The infection was successfully treated with catheter removal and intravenous amphotericin B.
Insights
A rare fungal infection, Penicillium peritonitis, complicated continuous ambulatory peritoneal dialysis (CAPD). This second reported case highlights successful treatment via catheter removal and antifungal therapy.
Area of Science:
- Nephrology
- Infectious Diseases
- Medical Mycology
Background:
- Continuous ambulatory peritoneal dialysis (CAPD) is a common renal replacement therapy.
- Infectious peritonitis is a significant complication of CAPD, often bacterial.
- Fungal peritonitis is a rare but serious complication of CAPD.
Observation:
- A second case of CAPD-related peritonitis caused by Penicillium species is presented.
- Fungal colonies were observed on the internal surface of the CAPD catheter.
- The patient presented with symptoms consistent with peritonitis.
Findings:
- The infection was successfully treated with the removal of the CAPD catheter.
- Intravenous administration of amphotericin B was effective in eradicating the fungal infection.
- This case underscores the importance of considering fungal pathogens in refractory or unusual peritonitis cases.
Implications:
- Early diagnosis and prompt treatment are crucial for managing fungal peritonitis in CAPD patients.
- Catheter removal is often a necessary component of successful treatment.
- Further research may be needed to elucidate the specific risk factors and optimal management strategies for fungal peritonitis in CAPD.