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Insulin-like growth factor-I and angiographically documented coronary artery disease
P Spallarossa1, C Brunelli, F Minuto
1Department of Internal Medicine, University of Genoa, Italy.
The American Journal of Cardiology
|January 15, 1996
Abstract:
In conclusion, we have reported an association between low IGF-I concentrations and CAD in relatively young men. This observation raises the possibility that IGF-I deficiency could be part of the polymetabolic syndrome. Whether a subnormal IGF-I production is due to growth hormone secretory abnormalities or to other metabolic reasons (e.g., insulin resistance or fat distribution, or both) is still unknown.