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An unrecognized renal physiologist: Friedrich Wöhler

G Richet

    American Journal of Nephrology
    |January 1, 1995
    PubMed
    Summary

    Friedrich Wöhler

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    Area of Science:

    • Chemistry
    • Physiology
    • Biochemistry

    Background:

    • Friedrich Wöhler's early work explored renal excretion and metabolism.
    • He investigated the excretion of 41 substances and their metabolic fates.
    • Wöhler's research touched upon the kidney's role in maintaining bodily homeostasis.

    Discussion:

    • Wöhler's 1824 publication predated his famous urea synthesis.
    • His findings linked substance excretion to metabolic processes.
    • The study highlighted the kidney's physiological functions.

    Key Insights:

    • Potassium salt excretion can be reduced or oxidized.
    • Urine pH can be acidic even with alkaline blood.
    • Water excretion is tied to the excretion rate of administered substances.

    Outlook:

    • Wöhler's early physiological research was foundational.
    • His work foreshadowed later discoveries in kidney function.
    • He could have been recognized as a leading physiologist.