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Aggressive squamous cell carcinomas developing in patients receiving long-term azathioprine
W W Bottomley1, G Ford, W J Cunliffe
1Department of Dermatology, Leeds General Infirmary, UK.
The British Journal of Dermatology
|September 1, 1995
Summary
Long-term azathioprine treatment may increase the risk of aggressive squamous cell carcinomas, especially with significant ultraviolet light (UVL) exposure. Patients on azathioprine require vigilant monitoring and sun protection to mitigate this risk.
Area of Science:
- Dermatology
- Oncology
- Immunosuppression
Background:
- Azathioprine is an immunosuppressive drug used for various dermatological conditions.
- Long-term use of immunosuppressants can be associated with an increased risk of certain cancers.
- Ultraviolet light (UVL) exposure is a known risk factor for skin cancer.