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Updated: Aug 14, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
Evaluation of an ACTBP2 ladder composed of 26 sequenced alleles
A Möller1, M Schürenkamp, B Brinkmann
1Institute of Legal Medicine, Westfälische Wilhelms-Universität, Münster, Germany.
Abstract:
A total of 90 alleles found in white Caucasians from North-West Germany were sequenced and 26 alleles chosen to construct a uniform and reliable allelic ladder for the STR system ACTBP2 (SE33). In addition 3 new aspects concerning the sequence structure were observed. Population studies were carried out on white Caucasians (n = 278) from North-West Germany using the new improved ladder. A total of 24 alleles and 14 "interalleles" were found and reproducible results obtained. No significant deviation from Hardy-Weinberg-equilibrium could be observed.
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