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The subcellular localization of 17 beta-hydroxysteroid dehydrogenase type 4 and its interaction with actin
1Max-Planck-Institut für experimentelle Endokrinologie, Hannover, Germany.
The Journal of Steroid Biochemistry and Molecular Biology
|December 1, 1995
Abstract:
The porcine 17 beta-hydroxysteroid dehydrogenase type 4 is the key enzyme for the inactivation of estradiol. Its localization in peroxisomes was proven by immunogold electron microscopy. Interactions of the 17 beta-hydroxysteroid dehydrogenase with cytoskeletal proteins might be mandatory for a topical assignment of enzymatic activity to defined subcellular compartments.