Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Neuronal migration disorders: clinical-radiological correlation]

D Guillén1, I Pascual-Castroviejo, V López Martín

  • 1Servicio de Neurología Pediátrica, Hospital Infantil La Paz, Madrid.

Revista De Neurologia
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epilepsy, neuroinflammation and cannabidiol What do we know thus far?

Frontiers in pharmacology·2026
Same author

Delphi consensus on recommendations for the treatment of spinal muscular atrophy in Spain (RET-AME consensus).

Neurologia·2022
Same author

Correction to: The starch-binding domain as a tool for recombinant protein purification.

Applied microbiology and biotechnology·2021
Same author

Bi-allelic mutations in EGR2 cause autosomal recessive demyelinating neuropathy by disrupting the EGR2-NAB complex.

European journal of neurology·2020
Same author

[Cannabidiol: its use in refractory epilepsies].

Revista de neurologia·2017
Same author

[Pharmacist's interview with type 2 diabetes: Development of a follow-up form].

Annales pharmaceutiques francaises·2017

This study correlates brain imaging in children with neuronal migration anomalies to their clinical symptoms. Findings suggest that the extent, location, and gray matter changes relate to neurological deficits.

Area of Science:

  • Neuroscience
  • Developmental Neuroscience
  • Pediatric Neurology

Context:

  • Neuronal migration disorders are congenital brain abnormalities.
  • These conditions can lead to significant neurological deficits.
  • Accurate diagnosis and understanding of these disorders are crucial for patient management.

Purpose:

  • To correlate neuroimaging findings with clinical manifestations in children diagnosed with neuronal migration anomalies.
  • To investigate the relationship between the characteristics of gray matter dysplasia and neurological deficits.

Summary:

  • This retrospective study analyzed 34 children with various neuronal migration disorders, including schizencephaly, lissencephaly, heterotopia, and hemimegalencephaly.
  • Diagnoses were confirmed using computerized tomography (CT) and magnetic resonance (MR) imaging.

Related Experiment Videos

  • The most severe clinical alterations observed were early-onset psychomotor delay and intractable seizures.

    • Impact:

    • The study highlights the correlation between the extension, location, and gray matter dysplasticity and the resulting neurological manifestations.
    • Findings can aid in predicting clinical outcomes and guiding therapeutic strategies for affected children.
    • Enhances understanding of the neurobiological basis of these complex developmental disorders.