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VIIIth cranial nerve involvement in sarcoidosis
1Princess Mary's Royal Air Force Hospital, Halton, Aylesbury, Bucks, UK.
The Journal of Laryngology and Otology
|November 1, 1995
Summary
Neurosarcoidosis can cause hearing loss and vertigo. This case study shows high-dose steroids and azathioprine effectively treated bilateral VIIIth nerve lesions in neurosarcoidosis.
Area of Science:
- Neurology
- Otolaryngology
Background:
- Neurosarcoidosis is a rare neurological disorder that can affect the auditory and vestibular systems.
- Hearing loss and vertigo are recognized, though uncommon, complications of neurosarcoidosis.
Observation:
- A case of sarcoidosis-induced hearing loss is presented.
- Bilateral VIIIth nerve lesions were identified using MRI with gadolinium enhancement.
Findings:
- The identified lesions showed a significant response to treatment.
- High-dose steroids and azathioprine led to symptomatic improvement and near-complete resolution of the lesions.
Implications:
- This case highlights the efficacy of aggressive immunosuppressive therapy in managing neurosarcoidosis affecting the VIIIth cranial nerve.
- Accurate lesion localization via MRI is crucial for effective treatment planning in neurosarcoidosis-related auditory and vestibular dysfunction.