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Updated: Aug 8, 2026

Analyzing and Building Nucleic Acid Structures with 3DNA
Published on: April 26, 2013
[Features of the primary structure of DNA from the synaptonemal complex of the golden hamster]
Abstract:
DNA of golden hamster synaptonemal complex (SC) was cloned and partially sequenced. Computer analysis was performed to compare the SC DNA sequences for different families of eukaryotic genomic DNA. SC DNA is homologous to LINE family and in contrast to genomic DNA is enriched with alternative (GT/CA)n sequences and palindromes. By its ability to form potential hairpin loops, SC DNA is similar to nuclear matrix-associated regions of DNA (MARs) and differs considerably from DNA of microsatellite loci. It is noteworthy that SC DNA, which is supposed to be involved in meiotic recombination, and DNA of immunoglobulin genes, involved in somatic recombination, are both enriched with palindromes. The discovered peculiarities of the structure of hamster SC DNA allow us to join it with rat SC DNA into a special family of rodent genomic DNA sequences.
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