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Updated: Feb 21, 2026

Author Spotlight: Generation of and Comparison Between Patient-Derived Gastric Organoids from Different Regions of the Stomach
Published on: January 26, 2024
[Cultivation of human gastric cancer tissue in diffusion chamber]
Abstract:
Under study was the morphology and proliferative activity of stomach cancer tissue from 10 patients under condition of its cultivation in diffusion chambers implanted in mice. Epithelial, fibroblastoid cells and cells of histiocyte type showed an active growth, greater proliferative activity being typical for epithelial cells. The mitotic cycle duration as evidenced by the data of the label dilution was longer than 30 hours. The time of the volume doubling calculated under some assumptions was, in the average, about 60 days for cancer of the stomach in man.
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