Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Osteoporosis. 1]

Z Fojtík1, J Mayer

  • 1II. Interní klinika FN, Brno-Bohunice.

Vnitrni Lekarstvi
|November 1, 1995
PubMed
Summary
This summary is machine-generated.

Osteoporosis is a disease where low bone mass and deterioration increase fracture risk. Understanding its pathogenesis and diagnosis is crucial for effective management.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Basic ethical aspects of living organ donation].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2003
Same author

[Hemophagocytic syndrome (case report and literature review)].

Vnitrni lekarstvi·2003
Same author

Anatomical study of the blood supply of the coxal bone: radiological and clinical application.

Surgical and radiologic anatomy : SRA·2002
Same author

Reduced nephrotoxicity of conventional amphotericin B therapy after minimal nephroprotective measures: animal experiments and clinical study.

The Journal of infectious diseases·2002
Same author

Structure of nanocrystalline anatase solved and refined from electron powder data.

Acta crystallographica. Section A, Foundations of crystallography·2002
Same author

Interleukin-2 activation of haematopoietic stem cells.

Acta medica Austriaca·2002
Same journal

Pharmacological profile of mepolizumab.

Vnitrni lekarstvi·2023
Same journal

Atypical form of Goodpasture's disease.

Vnitrni lekarstvi·2023
Same journal

Differentiated thyroid cancer - possible risks of treatment, suppressive therapy and adherence to current recommendations.

Vnitrni lekarstvi·2023
Same journal

Dyslipidemia - the known unknown.

Vnitrni lekarstvi·2023
Same journal

Internal comorbidities and complications of multiple sclerosis therapy - don't be caught off guard!

Vnitrni lekarstvi·2023
Same journal

Implications of highly suppressive treatment HIV infection.

Vnitrni lekarstvi·2023
See all related articles

Area of Science:

  • Bone Biology and Disease
  • Endocrinology
  • Gerontology

Context:

  • Osteoporosis is characterized by reduced bone mass and microarchitectural deterioration, leading to increased fracture risk.
  • Bone loss stems from disruptions in the continuous bone remodeling process in the adult skeleton.
  • Peak bone mass is influenced by genetics and nutrition during skeletal development.

Purpose:

  • To review current data on the pathogenesis and diagnosis of osteoporosis.
  • To elucidate the mechanisms underlying bone loss and fragility.
  • To provide insights into the cellular and hormonal regulation of bone remodeling.

Summary:

  • Low bone mass results from either insufficient bone formation during growth or excessive bone resorption during remodeling.

Related Experiment Videos

  • Bone remodeling, a cyclical process involving bone cells and mediated by hormones and cytokines, is critical for skeletal maintenance.
  • Disruptions in the remodeling cycle can lead to osteoporosis, a condition defined by low bone mass, tissue deterioration, and fragility.

    • Impact:

    • Enhanced understanding of osteoporosis pathogenesis can inform diagnostic strategies.
    • This review aids in identifying key factors contributing to bone fragility.
    • Insights into bone remodeling disruptions may guide future therapeutic interventions for osteoporosis.