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[Pharmacokinetics in liver cirrhosis]
Zeitschrift Fur Die Gesamte Innere Medizin Und Ihre Grenzgebiete
|January 1, 1977
Summary
Severe liver damage impairs drug metabolism and detoxification, which cannot be fully explained by plasma half-life alone. Certain drugs and their metabolites can worsen liver injury, making them contraindicated in liver disease patients.
Area of Science:
- Pharmacology
- Hepatology
- Toxicology