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Infantile osteopetrosis; bone marrow transplantation from a cousin donor
G M Taylor1, S P Dearden, A M Will
1Immunogenetics Laboratory, St Marys Hospital, Manchester.
Archives of Disease in Childhood
|November 1, 1995
Abstract:
The successful correction of infantile osteopetrosis in an Asian child by bone marrow transplantation (BMT) from an HLA-A,B matched cousin donor is reported. Retrospective HLA molecular analysis revealed that patient and donor were incompatible for HLA-DPB1. Donor type cells detected in the patient after transplantation indicate successful engraftment. The patient is currently alive and well.