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Ethanol decreases basal cytosolic-free calcium concentration in cultured skeletal muscle cells
M Cofán1, J Fernandez-Solà, J M Nicolás
1Department of Internal Medicine, Hospital Clínic, University of Barcelona, Spain.
Alcohol and Alcoholism (Oxford, Oxfordshire)
|September 1, 1995
Abstract:
We analysed the effect of ethanol on basal cytosolic-free calcium concentration ([Ca2+]i) in cultured rat myocytes. Ethanol caused a dose-dependent decrease of the resting [Ca2+]i. Removal of ethanol was followed by a transitory increase of [Ca2+]i above the basal level. In cells chronically exposed to ethanol, [Ca2+]i normalized to the previous level.