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Related Experiment Videos

[Laryngeal histoplasmosis]

R Fernández Liesa1, J Pérez Obón, T Ramírez Gasca

  • 1Servicio de ORL, Hospital Miguel Servet, Zaragoza.

Acta Otorrinolaringologica Espanola
|November 1, 1995
PubMed
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A case of laryngeal histoplasmosis, a fungal infection of the voice box, was successfully treated with Itraconazole. Diagnosis involved identifying Histoplasma capsulatum through histological examination of vocal cord tissue.

Area of Science:

  • Otolaryngology
  • Mycology
  • Infectious Diseases

Background:

  • Laryngeal mycosis is a rare fungal infection affecting the larynx.
  • Histoplasmosis, caused by Histoplasma capsulatum, typically affects the lungs but can manifest in other organs.

Observation:

  • A patient presented with symptoms indicative of laryngeal pathology.
  • Laryngoscopy revealed significant inflammation, including edema, erythema, and leukoplakia of the right vocal cord.

Findings:

  • Histopathological examination confirmed the presence of intracellular hyphae of Histoplasma capsulatum, establishing the diagnosis of laryngeal histoplasmosis.
  • The infection was localized to the vocal cord.

Implications:

  • This case highlights the importance of considering fungal infections in the differential diagnosis of laryngeal lesions.

Related Experiment Videos

  • Successful treatment with Itraconazole suggests its efficacy in managing laryngeal histoplasmosis.
  • Further research into the presentation and management of laryngeal mycoses is warranted.