[Clinical application of endoscopic injection of medication for stopping gastric bleeding]

The authors studied 40 patients with bleeding from peptic ulcer or gastric carcinoma, and evaluated the therapeutic effects of endoscopic injection of absolute alcohol and Bathroxobin. Among them, 20 patients were given absolute alcohol and the remaining 20 Bathroxobin (Reptilase). Absolute alcohol was injected submucosally at 4-6 pinpoints around the bleeding site (0.1-0.2ml/dose, total dose 0.5-1.2ml); Bathroxobin was injected similarly (1 kU/dose, total dose 0.5-1.0kU). Treatment failed in one patient receiving alcohol because of spouting artery bleeding and surgery was resorted to finally. The other 39 patients had successful stopping of the bleeding in one time. The effective rate is 97.5 percent (39/40) and the rate of re-bleeding is low. It is thus shown that endoscopic submucosal injection of absolute alcohol and Bathroxobin for stopping gastric bleeding is safe, simple and effective. However, more experience is needed in this respect.