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Gross bilateral reflux in infants: gradual decrease of initial detrusor hypercontractility

U Sillén1, M Bachelard, G Hermanson

  • 1Department of Pediatric Surgery, Children's Hospital, Goteborg, Sweden.

The Journal of Urology
|February 1, 1996
PubMed
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Followup urodynamic evaluation in boys with bilateral reflux shows resolution of detrusor hypercontractility and increased bladder capacity. These findings suggest improved bladder function over time in pediatric patients with vesicoureteral reflux.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Urodynamics

Background:

  • Vesicoureteral reflux (VUR) in children can present with abnormal bladder function, including low bladder capacity and detrusor hypercontractility.
  • Gross bilateral reflux requires careful monitoring of urodynamic patterns.

Purpose of the Study:

  • To investigate the longitudinal urodynamic patterns in boys diagnosed with gross bilateral vesicoureteral reflux.
  • To assess changes in bladder capacity and detrusor activity over time.

Main Methods:

  • Follow-up urodynamic evaluations were conducted on 11 boys.
  • Assessments were performed approximately 2 years after initial evaluations during infancy.

Main Results:

  • The majority of boys showed resolution of initial detrusor hypercontractility.

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  • Bladder capacity increased significantly, moving from below normal to high levels in most cases.
  • The prevalence of detrusor instability remained statistically unchanged.

    • Conclusions:

    • The urodynamic profile in older children with VUR often normalizes over time.
    • Follow-up urodynamics reveal a pattern consistent with typical findings in older children experiencing reflux.
    • These results highlight the dynamic nature of bladder dysfunction in pediatric VUR.