Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Simulation of chronic mitral regurgitation

R Razzolini1, P Viena, F Degan

  • 1Department of Hemodynamics, University of Padova Medical School, Italy.

Japanese Heart Journal
|September 1, 1995
PubMed
Summary

Mitral regurgitation causes left ventricle enlargement. This study predicts final left ventricular volumes and mass based on mitral regurgitation severity, with good accuracy in most patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of sacroiliitis on magnetic resonance enterography in Crohn's disease and its association with intestinal findings: a monocentric observational cross-sectional study.

Clinical and experimental medicine·2025
Same author

Onset of Schamberg Disease and Resolution of Alopecia Areata During Treatment of Atopic Dermatitis With Dupilumab.

Journal of investigational allergology & clinical immunology·2020
Same author

In vivo diagnosis of cardiac angiosarcoma by endomyocardial biopsy.

Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology·2015
Same author

Towards defining the role of drug eluting stents.

Minerva cardioangiologica·2008
Same author

Active versus borderline myocarditis: clinicopathological correlates and prognostic implications.

Heart (British Cardiac Society)·2002
Same author

Images in cardiovascular medicine. Coronary spasm resistant to intracoronary nitrates following successful stent implantation.

Italian heart journal : official journal of the Italian Federation of Cardiology·2002

Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Mitral regurgitation (MR) leads to left ventricular (LV) enlargement to compensate for volume overload.
  • LV mass increase in MR is influenced by regurgitant volume and other hemodynamic factors like contractility and arterial properties.

Purpose of the Study:

  • To develop a predictive model for final left ventricular volumes and mass in patients with mitral regurgitation.
  • To compare model predictions with actual clinical data to assess accuracy.

Main Methods:

  • Utilized data from patients with mitral regurgitation.
  • Developed a model to predict LV volumes and mass based on the severity of MR.
  • Validated predictions against real-world patient data.

Related Experiment Videos

Main Results:

  • The predictive model demonstrated good accuracy in estimating final LV volumes and mass for most patients.
  • Discrepancies between predicted and actual values may indicate advanced left ventricular decompensation.

Conclusions:

  • Predictive modeling is a valuable tool for understanding LV remodeling in mitral regurgitation.
  • Model accuracy supports its potential clinical utility in assessing disease progression and decompensation.